Lahorenoic Acids A−C, ortho-Dialkyl-Substituted Aromatic Acids from the Biocontrol Strain Pseudomonas aurantiaca PB-St2

Please use this identifier to cite or link to this item: http://digitalrepository.fccollege.edu.pk/handle/123456789/1090

Title:	Lahorenoic Acids A−C, ortho-Dialkyl-Substituted Aromatic Acids from the Biocontrol Strain Pseudomonas aurantiaca PB-St2
Authors:	Mehnaz, Samina Saleem, Rahman Shah Zaib Yameen, Basit Pianet, Isabelle Schnakenburg, Gregor Pietraszkiewicz, Halina Valeriote, Fred Josten, Michaele Sahl, Hans-Georg Franzblau, Scott G. Gross, Harald
Keywords:	Lahorenoic Acids Aromatic Acids Strain Pseudomonas aurantiaca
Issue Date:	12-Feb-2013
Publisher:	ACS publications
Citation:	doi.org/10.1021/np3005166 \| J. Nat. Prod. 2013, 76, 135−141
Series/Report no.:	J. Nat. Prod. 2013, 76, 135−141;
Abstract:	Three new aromatic acids, named lahorenoic acids A (1), B (2), and C (3), have been isolated along with the known compounds phenazine-1-carboxylic acid (4), 2- hydroxyphenazine-1-carboxylic acid (5), 2-hydroxyphenazine (6), 2,8-dihydroxyphenazine (7), cyclo-Pro-Tyr (8), cyclo-Pro Val (9), cyclo-Pro-Met (10), and WLIP (11) and charac terized from the biocontrol strain Pseudomonas aurantiaca PB St2. The structures of these compounds were deduced by 1D and 2D NMR spectroscopic and mass spectral data interpretation. Compounds 2, 4, and 7 showed moderate antibacterial activity against mycobacteria and other Gram positive bacteria, while 4 was also found to exhibit cytotoxic and antifungal properties.
URI:	http://localhost:8080/xmlui/handle/123456789/1090
Appears in Collections:	School of Life Sciences

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