Development and Validation of an HPLC Method for the Determination of Dexamethasone, Dexamethasone Sodium Phosphate and Chloramphenicol in Presence of Each Other in Pharmaceutical Preparations

Please use this identifier to cite or link to this item: http://digitalrepository.fccollege.edu.pk/handle/123456789/2273

Title:	Development and Validation of an HPLC Method for the Determination of Dexamethasone, Dexamethasone Sodium Phosphate and Chloramphenicol in Presence of Each Other in Pharmaceutical Preparations
Authors:	Saeed Iqbal, Mohammad Aslam Shad, Muhammad W. Ashraf, M. Bilal, Muhammad
Keywords:	Column liquid chromatography Corticosteroids Chloramphenicol
Issue Date:	Jan-2006
Publisher:	researchgate.net
Citation:	Iqbal, Mohammad & Shad, Muhammad & Ashraf, M. & Bilal, Muhammad & Saeed, M.. (2006). Development and Validation of an HPLC Method for the Determination of Dexamethasone, Dexamethasone Sodium Phosphate and Chloramphenicol in Presence of Each Other in Pharmaceutical Preparations. Chromatographia. 64. 219-222. 10.1365/s10337-006-0019-3.
Abstract:	An HPLC method for the determination of dexamethasone, dexamethasone sodium phosphate and chloramphenicol in presence of each other in pharmaceutical preparations has been developed using a Shim-Pack CLC-ODS column (6.0 · 150 mm2). These analytes were separated under isocratic conditions. Various chromatographic parameters including linearity, precision and accuracy have been evaluated. The method was found to be suitable for analysis of these drug substances in presence of each other. The run time was less than 15 min. This method is suitable for application to various dosage forms.
URI:	http://202.142.177.21/handle/123456789/2273
Appears in Collections:	Chemistry Department

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